| Band | Years | Genre | | Band | Years | Genre |
| S.E.S (2) | | | | Soft Machine (2) | | |
| S.O.A.P. (3) | | | | Softies, The (4) | | |
| S.P.O.C.K (2) | | | | Some Odd Reason (1) | | |
| S Club (55) | - 2003 | | | Something Corporate (43) | 2000 - | Emo |
| S Club Juniors (4) | 2002 - | Pop | | Son Volt (1) | | Alternative Country |
| Saafir (1) | | | | Sonic Youth (78) | 1981 - | Rock |
| Sacrifice Isaac (1) | | | | Sonicflood (14) | 1998 - | Christian Rock |
| Sacrifist (3) | | | | Sonics, The (3) | 1963 - 1967 | Garage Rock |
| Sade (16) | | | | Sonny and Cher (7) | 1964 - 1974 | Folk-Rock |
| Safka, Melanie (11) | | | | Sonny Crocket (1) | | |
| Saga (4) | | | | Sons of Champlin (2) | | |
| Sailor (6) | | | | Sons of Harmony (4) | | |
| Saint (1) | | | | Sons of Maxwell (3) | | |
| Saint Etienne (6) | | | | Sons of Prozac (2) | 1999 - | Hip-Hop |
| Saint Sophia (3) | | | | Sons of the Desert (5) | | |
| Saints, The (2) | | | | Sons of the Pioneers (3) | | |
| Salad (2) | | | | Sons of the San Joaquin, The (4) | | |
| Saloon (1) | | Pop | | Sorcery (3) | | |
| Salt-N-Pepa (3) | | | | Soreazis (3) | | |
| Sam and Dave (5) | | Soul | | Soul Asylum (21) | 1983 - | Rock |
| Sam the Sham and the Pharaohs (6) | | Garage Rock | | Soul Coughing (9) | | |
| Samantha 7 (5) | | | | Soul Miners Daughter (1) | | |
| Samiam (3) | | | | Soulbelly (1) | | |
| Sammie (1) | | | | Soulcracker (5) | | |
| Samples, The (3) | | | | soulDecision (47) | | |
| Sanctity (2) | | | | Soulfly (14) | 1997 - | Rock |
| Sand Rubies (1) | | | | Soulwax (6) | | |
| Sandra (4) | | | | Sound Tribe Sector 9 (5) | | Jam Rock |
| Santana (24) | | | | Soundgarden (28) | 1984 - 1997 | Grunge |
| Sarax (2) | | | | Sounds, The (5) | | Electroclash |
| Sash (54) | 1995 - | Euro-Dance | | Soup Dragons, The (3) | | Madchester |
| SatanicBlack (2) | | | | South Sixty Five (8) | | |
| Savage Garden (44) | 1997 - 2001 | Pop | | Southern Culture on the Skids (4) | | Alternative Country |
| Savannah (2) | | | | Southern Death Cult, The (12) | 1984 - 1995 | Rock |
| Savatage (16) | | Heavy Metal | | Southern Rock Allstars (3) | | |
| Save Ferris (14) | 1995 - | Ska | | Southside Johnny and the Asbury Jukes (20) | 1975 - | Rhythm and Blues |
| Saves the Day (10) | 1997 - | Emo | | Soviet (2) | | Electroclash |
| Saville (5) | | | | Space (6) | | Alternative Rock |
| Saving Boy Wonder (2) | | | | Spacehog (6) | | |
| Saviour Machine (2) | | Christian Rock | | Spacemen 3 (10) | 1982 - 1991 | Psychedelic Rock |
| Sawdoctors, The (2) | | | | Spain (2) | | |
| Sawyer Brown (6) | | | | Spandau Ballet (8) | | |
| Scabs, The (11) | 1993 - | Funk | | Spanky and Our Gang (4) | | |
| Scared Weird Little Guys (2) | | | | Sparklehorse (9) | | |
| Sci-Fi Prodigy (2) | | Rock | | Sparks (6) | | |
| Scissor Sisters (8) | | | | Spear of Destiny (2) | | |
| Scooter (4) | | | | Spearhead (1) | 1994 - | |
| Scorpions (12) | | | | Specials, The (6) | | |
| Screaming Jets (2) | | | | Spectrum (1) | | |
| Screaming Trees (15) | | | | Speed McQueen (2) | | |
| Screeching Weasel (5) | | | | Spencer, Jon (7) | | |
| Scritti Politti (3) | | | | Spice Girls (105) | 1996 - | Pop |
| Sea and Cake, The (5) | | | | Spiderbait (9) | | |
| Sea Hags (3) | | Hair Metal | | Spiller (5) | | |
| Seafood (3) | | Rock | | Spin Doctors (11) | | |
| Seagull Screaming Kiss Her Kiss Her (2) | | Rock | | Spinal Tap (18) | 1964 - | Hard Rock |
| Seahorses, The (3) | | | | Spineshank (4) | Feb 1996 - | Alternative Rock |
| Seanachie (4) | | Celtic | | Spiraling (0) | | |
| Searchers, The (1) | | British Invasion | | Spirit Creek (3) | 1996 - | Christian Rock |
| Seawind (45) | 1974 - 1982 | Jazz-Funk | | Spirits of Eve (1) | | |
| Sebadoh (6) | | | | Spiritualized (13) | | |
| Second Chapter of Acts (30) | 1972 - 1988 | Christian Rock | | Splender (6) | | |
| Secret Garden (10) | | Neo-Classical | | Split Enz (3) | 1972 - 1985 | New Wave |
| Secret Hate (3) | | | | Splitsville (2) | | |
| Secret Secret (1) | | | | Spock's Beard (6) | | |
| Seefeel (2) | | | | Sponge (2) | | |
| Seekers, The (6) | | Folk | | Spoo Monkeys (2) | | |
| Selena (23) | | | | Spoon (3) | | |
| Self (8) | | | | Sporty Thievz (3) | | |
| Selzers, The (1) | | | | Spread (1) | | |
| Semisonic (11) | | | | Springbok Nude Girls (1) | | |
| Sentenced (2) | | | | Squeeze (6) | | |
| September When, The (1) | | Pop | | Squirrel Nut Zippers (31) | 1993 - | Jazz |
| Sepultura (26) | 1984 - | Heavy Metal | | SR-71 (6) | | |
| Serenity (3) | | | | St. Lunatics (3) | | Hip-Hop |
| Serial Joe (14) | | | | St. Madness (3) | | |
| Servo (3) | 1998 - | Blues-Rock | | Stabbing Westward (12) | | |
| Servotron (2) | | | | Stage Dolls (3) | | Hair Metal |
| Seven Mary Three (4) | 1992 - | Alternative Rock | | Staind (16) | 1995 - | Rock |
| Seven Nations (5) | | | | Stampeders, The (4) | | |
| Sevendust (8) | | | | Stampin' Ground (7) | 1995 - | Hardcore Punk |
| Severed Heads (10) | | | | Stan Kenton Orchestra (9) | Jun 1941 - Aug 1979 | Post-Bop |
| Sex Gang Children (10) | | Goth Rock | | Standells, The (6) | | Garage Rock |
| Sex Pistols (26) | 1975 - 1978 | Rock | | Standing In The Sun (1) | | |
| Shad Hills Band (1) | | | | Staple Singers, The (8) | | |
| Shadow Gallery (5) | 1992 - | Progressive Rock | | Starflyer 59 (49) | | Shoegaze |
| Shadows, The (10) | | | | Starmarket (9) | | |
| Shadows Fall (1) | | Heavy Metal | | Starsailor (5) | | Alternative Rock |
| Shadows of Knight, The (4) | | Garage Rock | | Starship (10) | | Rock |
| Shaggy (9) | | | | Start, The (12) | August 23, 1998 - | Punk |
| Shakatak (2) | | | | Starting Line, The (28) | 1999 - | Punk |
| Shakespear's Sister (9) | | | | State of Quo (3) | | |
| Shamen, The (2) | | | | Static-X (11) | | |
| She Moves (2) | | Rhythm and Blues | | Static in Stereo (6) | | |
| Shed 7 (2) | | | | Statler Brothers, The (5) | | |
| SHeDAiSY (12) | | | | Status Quo (25) | | British Invasion |
| Shenandoah (16) | 1984 - | Country | | Steadman (2) | | |
| Sherbet (2) | Apr 1969 - 1984 | Classic Rock | | Steamhammer (15) | 1968 - 1972 | Progressive Rock |
| Shihad (4) | | Rock | | Steel Breeze (2) | | |
| Shins, The (1) | | | | Steeleye Span (9) | 1970 - 2001 | British Folk |
| Shirelles, The (6) | | Motown | | Steelheart (3) | | Hair Metal |
| Shivaree (2) | | | | Steely Dan (20) | | Rock |
| Shocking Blue (1) | | | | Steppenwolf (7) | | Rock |
| Shoe Suede Blues (4) | 1994 - | Electric Blues | | Steps (34) | 1997 - 2001 | Pop |
| Shonen Knife (22) | | | | Stereo, The (3) | | |
| Showoff (2) | | | | Stereo 360 (4) | | Indie Rock |
| Shri (2) | | | | Stereo Deluxx (4) | | |
| Shriekback (4) | | | | Stereo MC's (1) | | House |
| Shroud, The (2) | | | | Stereo Total (3) | | Rock |
| Sicko (3) | | | | Stereolab (14) | | |
| Sierra (3) | | | | Stereophonics (37) | 1996 - | Rock |
| Sigue Sigue Sputnik (7) | | | | Stian (1) | | |
| Sigur Rós (9) | | | | Stickchap (4) | | |
| Sikth (5) | 2001 - | Grindcore | | Stiff Little Fingers (3) | 1977 - | Punk |
| Silkk the Shocker (2) | | | | Sting (39) | | Pop |
| Silly Wizard (14) | 1971 - 1988 | Scottish Folk | | Stompers, The (2) | | |
| Silver Beatles, The (566) | 1957 - 1970 | Rock | | Stone 588 (2) | | |
| Silver Jews (9) | | | | Stone Coyotes, The (2) | | |
| Silver Scooter (8) | Aug 1995 - Dec 2001 | Indie Rock | | Stone Roses, The (14) | | |
| Silver Sun (4) | 1995 - | Power Pop | | Stone Sour (48) | | Heavy Metal |
| Silverchair (68) | 1994 - | Rock | | Stone Temple Pilots (13) | | |
| Silverwind (2) | | Contemporary Christian | | Stoneman Family, The (0) | | Country |
| Simon and Garfunkel (23) | 1964 - 1970 | Rock | | Stooges, The (2) | 1967 - 1973 | Rock |
| Simon and Milo (4) | | Techno | | Strangelove (3) | | |
| Simon Apple (5) | | | | Strangers with Candy (15) | | |
| Simon Says (6) | | | | Stranglers, The (3) | | |
| Simple Minds (10) | | | | Strathclyde Police Pipers, The (1) | 1991 - 1991 | Pipe and Drum |
| Simply Red (4) | 1984 - | Rock | | Stratovarius (19) | 1984 - | Heavy Metal |
| Sinboy (4) | | | | Strawberry Alarm Clock (2) | | |
| Since August (4) | 1997 - | Rock | | Strawberry Switchblade (3) | | |
| Sinisstar (3) | | Heavy Metal | | Strawbs, The (2) | | |
| SinOmatic (2) | | | | Stray Cats (35) | 1979 - 1994 | Rockabilly |
| Siouxsie and the Banshees (8) | 1976 - 1996 | Rock | | Streetnix (24) | 1991 - 2002 | A Cappella |
| Sir Mix-A-Lot (2) | | | | Streets (4) | 1982 - 1985 | Rock |
| Sissel (3) | | | | Streetwalkers (2) | | |
| Sister 2 Sister (9) | | | | Stretch Princess (2) | | |
| Sister Moon (1) | | | | Stretford (2) | | |
| Sisters of Mercy, The (21) | | | | String Cheese Incident (6) | | |
| Sitze Family, The (2) | | | | Stroke 9 (6) | | |
| Six by Seven (2) | | | | Strokes, The (9) | | |
| Six Feet Under (3) | | Heavy Metal | | Strung Out (2) | | |
| Sixpence None the Richer (18) | 1993 - | Christian Rock | | Stryper (12) | | |
| Sixteen Deluxe (4) | | | | Studiotone (4) | | Rock |
| Sixteen Horsepower (20) | 1993 - | Alternative Country | | Style Council (4) | | Pop |
| Skabs, The (1) | | | | Stymeed (2) | | |
| Skandal (6) | | | | Styx (86) | 1970 - | Arena Rock |
| Skatalites, The (4) | 1963 - 1965 | Reggae | | Sublime (78) | - May 1996 | Ska |
| Skeptics (2) | | | | Substance, The (4) | | |
| Skid Row (9) | | | | Subtonics, The (2) | | |
| Skillet (17) | | Christian Rock | | Suddenly, Tammy (6) | | |
| Skindealer (1) | | Industrial Rock | | Suede (73) | | |
| Skindive (3) | | | | Sugababes (14) | | Pop |
| Skinny Puppy (4) | 1982 - 1996 | Rock | | Sugar (8) | | |
| Skins, The (1) | | | | Sugar Jones (9) | | |
| Skulker (2) | | | | Sugar Ray (53) | 1992 - | Alternative Rock |
| Skunk Anansie (14) | | | | Sugar Shack (2) | | |
| Sky (3) | | | | Sugarcubes, The (5) | | Alternative Rock |
| Sky Kings, The (2) | | | | Sugarcult (2) | | |
| Skyhooks (0) | | Glam Rock | | Suicidal Tendencies (5) | | |
| Slade (7) | | | | Suicide (15) | | |
| Slainte Mhath (3) | | | | Suicide Machines, The (2) | | |
| Slaughter (8) | | | | Sukia (6) | 1995 - | Electronica |
| Slayer (16) | | | | Sum 41 (52) | 1996 - | Punk |
| Sleater-Kinney (19) | | | | Sun Ra (19) | | |
| Sleeper (2) | | | | Sundays, The (9) | | |
| Slick Idiot (2) | | Industrial Rock | | Sunk Loto (1) | | Rock |
| Slip, The (5) | | Jam Rock | | Sunny Day Real Estate (16) | | Emo |
| Slipknot (86) | 1995 - | Heavy Metal | | Sunscreem (3) | | |
| Slits, The (2) | | Punk | | Sunshine Skiffle Band (1) | c. 1980s - | Skiffle |
| Sloan (7) | 1991 - | Rock | | Super Furry Animals (18) | | |
| Slobberbone (3) | | Alternative Country | | Supercharger (2) | | |
| Sloppy Meat Eaters (2) | | | | Superchunk (2) | | |
| Slow Train Coming (2) | 1999 - | Rock | | Supergrass (12) | | |
| Slowdive (5) | | | | Superheist (2) | | |
| Slugwrench (4) | | | | Superjesus, The (4) | | |
| Sly and the Family Stone (5) | | | | Supernaturals, The (2) | | |
| Smakhead (2) | | | | Supersnazz (1) | | Garage Rock |
| Small Faces, The (3) | | | | Supertones, The (23) | 1996 - | Ska |
| Smap (6) | | | | Supertramp (28) | 1969 - | Progressive Rock |
| Smash Mouth (11) | | | | Supremes, The (7) | | Motown |
| Smashing Pumpkins (153) | 1998 - 2000 | Rock | | Sureburn (2) | | |
| Smile (1) | 1969 - 1971 | Rock | | Survivor (2) | | |
| Smithereens (6) | | | | Swans (6) | 1982 - 1997 | Rock |
| Smiths, The (30) | 1982 - August 1987 | Alternative Rock | | Sweeney Todd (4) | | Garage Rock |
| Smog (5) | | | | Sweet, The (7) | | Glam Rock |
| Smokie (4) | | | | Sweet 75 (3) | | |
| Smokin' Armadillos (6) | | | | Sweet Comfort Band (1) | 1973 - 1985 | Christian Rock |
| Snafu (6) | 1973 - 1976 | Rock | | Sweet Honey in the Rock (5) | | |
| Snake River Conspiracy (2) | | | | Sweethearts of the Rodeo (4) | | |
| Sneaker Pimps (5) | | | | Sweetwater (3) | | |
| SNFU (14) | 1982 - | Punk | | Swervedriver (4) | | |
| Snow (4) | | | | Swing Out Sister (2) | | |
| So Solid Crew (1) | | Garage House | | Swingle Singers, The (3) | | Vocal Jazz |
| Soak (5) | May 1994 - Aug 2000 | Hard Rock | | Swirlies, The (2) | | Shoegaze |
| Sobs, The (3) | 2000 - | Ambient | | Swirling Eddies, The (29) | 1975 - | Christian Rock |
| Social Deviantz (8) | | | | Switchblade Symphony (5) | | |
| Social Distortion (5) | | | | Switchfoot (22) | | Christian Rock |
| Socialburn (6) | | Alternative Rock | | Sylver (2) | | Euro-Dance |
| Soda Ash (1) | | | | Symposium (4) | 1996 - 1999 | |
| Soda Stereo (2) | | | | Synthetics, The (33) | 1987 - | Rock |
| Soft Boys, The (7) | | New Wave | | System of a Down (17) | | Rock |
| Soft Cell (7) | 1980 - 1984 | Post-Punk | | Systematic (3) | | |
